Folic acid must be converted to its active forms to be used by the body.* This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body´s needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.*
Because deficiencies of folic acid have been linked to low-birth-weight infants and neural tube defects, folic acid requirements double during pregnancy.* The Centers for Disease Control and Prevention recommends folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant.* Supplementation with the more active form may be preferable.*
In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine.* Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.*
It is important for women of childbearing age to get enough folic acid – not just those who are planning to become pregnant.* Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day – especially before conception and during early pregnancy.*
* Value not establish
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
Suggested Use: Take 1 capsule one to three times daily or as recommended by a health-care practitioner.
WARNINGS. Do not exceed recommended serving. Keep out of the reach of children. The product is used as part of a varied and balanced diet and a healthy lifestyle. Food supplements are not intended to be a substitute for a varied diet.